Research Article
1 Consultant Paediatrician/Deputy Director of Research, Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria
2 Senior Research Fellow, Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria
3 Principal Medical Officer, Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria
4 Senior Medical Officer, Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria
5 Biostatistician/ Medical Officer, Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria
6 Medical Officer, Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria
7 Lecturer/Nutritionist, Federal College of Education (Technical) Akoka, Lagos, Nigeria
8 Consultant Paediatrician/Research Fellow, Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria
Address correspondence to:
Odubela Oluwatosin O
MBChB, MScPH, 6 Edmond Crescent, Yaba, Lagos,
Nigeria
Message to Corresponding Author
Article ID: 100009P05DN2021
Aims: This study sought to evaluate the prevalence of hypertension and its associated factors among adolescents living with human immunodeficiency virus (HIV) in Lagos, Nigeria.
Methods: A cross-sectional study involving adolescents attending an antiretroviral therapy (ART) clinic in Lagos was enrolled in the study. Case record form was developed to capture data on socio-demographic, clinical, laboratory, and treatment parameters of Participants. Blood pressure readings, waist circumference, and fasting lipid profiles of participants were also obtained. Hypertension was defined as a blood pressure reading ≥95th percentile for age, sex, and height or readings above 120/80 mmHg irrespective of age or gender by the Fourth Report on the Diagnosis, Evaluation, and Treatment of High Blood Pressure in Children and Adolescents.
Results: One hundred and fifty-three adolescents participated in the study with males accounted for 52% of the study population. The majority of participants were in secondary school (79.7%), had both parents alive (73.2%), and acquired HIV infection through vertical transmission (99.3%). The prevalence of hypertension was 10.5%. The predictive risk factors for hypertension were older age [odds ratio (OR) 1.557, 95% confidence interval (CI) 0.344–7.040], waist circumference (OR 6.435, 95% CI 1.396–29.666), duration on ART >8 years (OR 1.308, 95% CI 0.332–5.153), and dyslipidemia (OR 2.942, 95% CI 0.726–11.914). However, only waist circumference was statistically significantly associated with hypertension (p < 0.05).
Conclusion: Our study revealed a high prevalence of hypertension among adolescents living with HIV. There is a need for regular monitoring of blood pressure and associated risk factors during routine care.
Keywords: Adolescents, Blood pressure, HIV, Hypertension, Lagos
David Agatha N - Substantial contributions to conception and design, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Gbaja-Biamila Titilola A - Substantial contributions to conception and design, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Odubela Oluwatosin O - Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Musari-Martins Tomilola E - Acquisition of data, Analysis of data, Revising it critically for important intellectual content, Final approval of the version to be published
Ezemelue Priscilla N - Analysis of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Opaneye Babasola A - Acquisition of data, Analysis of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Lagunju Mofeoluwa M - Acquisition of data, Analysis of data, Drafting the article, Final approval of the version to be published
Arije Doyinsola M - Acquisition of data, Analysis of data, Drafting the article, Final approval of the version to be published
Abubakar Rufai A - Acquisition of data, Interpretation of data, Drafting the article, Final approval of the version to be published
Ezechi Lilian O - Analysis of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Salako Abideen O - Substantial contributions to conception and design, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
AcknowledgmentsOur sincere appreciation to adolescents attending the ART clinic at the Nigerian Institute of Medical Research, Yaba, Lagos for their cooperation and continued trust to provide comprehensive medical care. Appreciation to the nurses, pharmacists, counsellors, and record officers of the clinic.
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2021 David Agatha N et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.